Primary Identifier | MGI:2448561 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 240255 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 3'-5' RNA helicase activity; N6-methyladenosine-containing RNA reader activity; and RNA binding activity. Involved in germline cell cycle switching, mitotic to meiotic cell cycle; oocyte development; and spermatid development. Located in cytoplasm and ribonucleoprotein granule. Is expressed in brain; gonad; intestine; and liver. Orthologous to human YTHDC2 (YTH N6-methyladenosine RNA binding protein C2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female and male infertility with arrested meiosis and small gonads. [provided by MGI curators] |