Primary Identifier | MGI:106264 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 28105 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-tubulin binding activity and ubiquitin-protein transferase activity. Involved in regulation of cell cycle. Acts upstream of or within acrosome reaction. Located in acrosomal vesicle. Is expressed in extraembryonic component; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human TRIM36 (tripartite motif containing 36). PHENOTYPE: Male mice for a null allele exhibit normal fertility. [provided by MGI curators] |