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Protein Coding Gene : Tnfaip8 tumor necrosis factor, alpha-induced protein 8
Primary Identifier  MGI:2147191 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  106869
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables molecular sequestering activity and small molecule binding activity. Acts upstream of or within defense response to Gram-positive bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including brain ventricular layer; choroid plexus; musculoskeletal system; respiratory system; and thymus primordium. Orthologous to human TNFAIP8 (TNF alpha induced protein 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to induced colitis. [provided by MGI curators]
  • synonyms:
  • predicted gene 10539,
  • expressed sequence AA987150,
  • E130304C20Rik,
  • Gg2-1,
  • ENSMUSG00000073567,
  • Tipe,
  • Gm10539,
  • Ssc-2,
  • MGI:3642692,
  • AA987150,
  • predicted gene, ENSMUSG00000073567,
  • Nded,
  • RIKEN cDNA E130304C20 gene,
  • tumor necrosis factor, alpha-induced protein 8,
  • Tnfaip8
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

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0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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