Primary Identifier | MGI:1914472 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 67222 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in maturation of SSU-rRNA. Located in nucleus. Is expressed in several structures, including axial musculature; genitourinary system; neural ectoderm; orbito-sphenoid; and submandibular gland primordium. Orthologous to human SRFBP1 (serum response factor binding protein 1). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic growth retardation and complete embryonic lethality before implantation. In vitro, embryos fail to hatch from the zona pellucida and die after 3 days in culture. [provided by MGI curators] |