| Primary Identifier | MGI:2147363 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 240332 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables L-proline transmembrane transporter activity. Acts upstream of or within proline transmembrane transport. Predicted to be located in synaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; presynaptic membrane; and synaptic vesicle membrane. Is expressed in brain; early conceptus; metanephros; and secondary oocyte. Orthologous to human SLC6A7 (solute carrier family 6 member 7). PHENOTYPE: Mice homozygous for one null allele display reduced uptake of L-proline in the brain, reduced responses to novelty, and impaired extinction of spatial memory. Mice homozygous for a second null allele display partial preweaning lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
