Primary Identifier | MGI:88360 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 12590 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity. Involved in regulation of somitogenesis. Acts upstream of or within anterior/posterior pattern specification; bone morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; embryo ectoderm; embryo mesenchyme; genitourinary system; and intestine. Orthologous to human CDX1 (caudal type homeobox 1). PHENOTYPE: Homozygous mutation of this gene results in abnormalities of the basiocciptal bone, vertebrae, and ribs. [provided by MGI curators] |