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Protein Coding Gene : Csnk1a1 casein kinase 1, alpha 1
Primary Identifier  MGI:1934950 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  93687
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein serine/threonine kinase activity. Involved in negative regulation of NLRP3 inflammasome complex assembly and protein phosphorylation. Acts upstream of or within cell morphogenesis. Located in ciliary basal body and spindle. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; endocrine gland; metanephros; retina nuclear layer; and thymus primordium. Orthologous to human CSNK1A1 (casein kinase 1 alpha 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality. [provided by MGI curators]
  • synonyms:
  • 5430427P18Rik,
  • 4632404G05Rik,
  • MGI:1914042,
  • Csnk1a1,
  • RIKEN cDNA 2610208K14 gene,
  • 2610208K14Rik,
  • MGI:1915311,
  • MGI:1926085,
  • RIKEN cDNA 5430427P18 gene,
  • RIKEN cDNA 4632404G05 gene,
  • casein kinase 1, alpha 1,
  • CK1a
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