Primary Identifier | MGI:1928397 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 56069 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity. Acts upstream of or within positive regulation of cytokine production involved in inflammatory response. Predicted to be located in extracellular space. Is expressed in several structures, including central nervous system; dorsal root ganglion; limb; limb bud; and trunk. Orthologous to human IL17B (interleukin 17B). PHENOTYPE: Mice homozygous for a gene trap allele exhibit increased susceptibility to DDS-induced colitis and Citrobacter rodentium infection. [provided by MGI curators] |