| Primary Identifier | MGI:1891408 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 225631 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including negative regulation of transforming growth factor beta receptor signaling pathway; peripheral nervous system neuron development; and positive regulation of mesenchymal stem cell migration. Predicted to be located in actin cytoskeleton and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future brain; genitourinary system; gut; and retina. Orthologous to human ONECUT2 (one cut homeobox 2). PHENOTYPE: Homozygous mutation of this gene results in abnormal bile duct development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
