Primary Identifier | MGI:1917473 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 70223 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable CCR3 chemokine receptor binding activity; asparagine-tRNA ligase activity; and protein dimerization activity. Predicted to be involved in asparaginyl-tRNA aminoacylation; cell migration; and cerebral cortex development. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human NARS1 (asparaginyl-tRNA synthetase 1). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts do not hatch from the zona pellucida or form outgrowths after 3 days in culture. [provided by MGI curators] |