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ncRNA Gene : Mir122 microRNA 122
Primary Identifier  MGI:2676805 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  387231
Mgi Type  miRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including BMP signaling pathway; erythrocyte differentiation; and multicellular organismal-level iron ion homeostasis. Part of RISC complex. Is expressed in embryo; liver; and lung. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MIR122 (microRNA 122).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit steatohepatitis with fibrosis and hepatocellular carcinoma. [provided by MGI curators]
  • synonyms:
  • microRNA 122,
  • microRNA 122b,
  • Mir122,
  • Mir122a,
  • mmu-mir-122,
  • MGI:2676806,
  • Mirn122a,
  • Mir122b,
  • Mirn122b,
  • microRNA 122a,
  • mmu-mir-122a
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