Primary Identifier | MGI:2149728 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 114663 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable inositol monophosphate 1-phosphatase activity and protein homodimerization activity. Predicted to be involved in inositol metabolic process; response to lithium ion; and signal transduction. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human IMPA2 (inositol monophosphatase 2). PHENOTYPE: Mice homozygous for a null gene trap mutation do not exhibit an overt mutant phenotype. Male mice homozygous for a knock-out alle exhibit increased prepulse inhibition. [provided by MGI curators] |