| Primary Identifier | MGI:1915416 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 68166 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable microtubule binding activity. Involved in several processes, including cytoskeleton organization; cytoskeleton-dependent cytokinesis; and intracellular transport. Acts upstream of or within Golgi vesicle transport; behavioral fear response; and dendritic spine development. Located in Golgi apparatus; cell cortex; and cytoplasmic vesicle membrane. Colocalizes with cleavage furrow. Is expressed in several structures, including central nervous system; genitourinary system; intestine; liver; and spleen. Orthologous to human SPIRE1 (spire type actin nucleation factor 1). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile with normal brain anatomy and intact visual and motor functions in both sexes, but show a male-specific increase in contextual and cued fear memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
