| Primary Identifier | MGI:3645984 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 664805 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SMAD binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cerebellar Purkinje cell differentiation; regulation of neural precursor cell proliferation; and regulation of signal transduction. Located in nucleus. Is expressed in brain; dorsal root ganglion; and spinal cord. Orthologous to human SKOR2 (SKI family transcriptional corepressor 2). PHENOTYPE: Mice homozygous for null mutations display neonatal and postnatal lethality, abnormal cerebellum development, and abnormal Purkinje cell differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
