Primary Identifier | MGI:1924234 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 71206 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity. Predicted to be involved in microtubule severing. Predicted to be located in cytoplasm; microtubule; and spindle pole. Orthologous to human KATNAL2 (katanin catalytic subunit A1 like 2). PHENOTYPE: Homozygous mutations in this gene result in male sterility associated with multiple anomalies in spermatogenesis, including defects in sperm tail growth, sperm head shaping, acrosome attachment, and sperm release. Males homozygous for a null allele are sterile and show oligoasthenoteratozoospermia. [provided by MGI curators] |