Primary Identifier | MGI:1096566 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 17344 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; SUMO transferase activity; and ubiquitin protein ligase binding activity. Acts upstream of or within DNA-templated transcription; protein sumoylation; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2). PHENOTYPE: An uncharacterized gene trap insertion does not result in an obvious phenotype although abnormalities are reported in the testes. [provided by MGI curators] |