Primary Identifier | MGI:1926953 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 67655 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity; TFIIF-class transcription factor complex binding activity; and Tat protein binding activity. Predicted to be involved in several processes, including exit from mitosis; negative regulation of cell growth involved in cardiac muscle cell development; and positive regulation by host of viral transcription. Predicted to be located in microtubule cytoskeleton; midbody; and nucleoplasm. Predicted to be part of protein-containing complex. Is expressed in several structures, including heart; liver; lung; nervous system; and spleen. Orthologous to human CTDP1 (CTD phosphatase subunit 1). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality with increased cell apoptosis. [provided by MGI curators] |