Primary Identifier | MGI:1340029 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 17771 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in male meiotic nuclear division and spermatogenesis. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including adrenal gland; gonad; heart; liver; and lung. Orthologous to human TESMIN (testis expressed metallothionein like protein). PHENOTYPE: Homozygous null mutations of this gene lead to male infertility due to arrested spermatogenesis at the pachytene stage. Male mice expressing a truncated protein that cannot interact with LIN9 phenocopy the defects observed in homozygous null males. [provided by MGI curators] |