| Primary Identifier | MGI:95637 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 14419 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable galanin receptor activity; galanin receptor binding activity; and neuropeptide hormone activity. Acts upstream of or within nervous system development; neuropeptide signaling pathway; and parental behavior. Predicted to be located in neuronal cell body. Predicted to be active in extracellular space and secretory granule. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and heart. Human ortholog(s) of this gene implicated in familial temporal lobe epilepsy 8 and opiate dependence. Orthologous to human GAL (galanin and GMAP prepropeptide). PHENOTYPE: Homozygous inactivation of this gene leads to alterations in neuroendocrine homeostasis, prolactin release, lactotroph number, mammary gland maturation, lactation, susceptibility to neuronal excitotoxicity and induced seizures, sensory neuron developmentand regeneration, and long term potentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
