Primary Identifier | MGI:1345963 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 23789 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Arp2/3 complex binding activity; actin filament binding activity; and identical protein binding activity. Predicted to be involved in several processes, including actin filament organization; cellular response to platelet-derived growth factor stimulus; and regulation of lamellipodium morphogenesis. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; heart and pericardium; nasal epithelium; nervous system; and septum transversum. Orthologous to human CORO1B (coronin 1B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal mast cell degranulation. [provided by MGI curators] |