| Primary Identifier | MGI:1100865 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 19653 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR binding activity and pre-mRNA binding activity. Involved in circadian regulation of translation; entrainment of circadian clock by photoperiod; and regulation of nucleocytoplasmic transport. Acts upstream of or within several processes, including insulin secretion involved in cellular response to glucose stimulus; regulation of gene expression; and regulation of insulin receptor signaling pathway. Located in nucleolus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human RBM4 (RNA binding motif protein 4). PHENOTYPE: Mice homozygous for a null mutation display reduced postnatal body weight, decreased insulin levels, smaller pancreatic islets and impaired glucose tolerance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
