Primary Identifier | MGI:3026882 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 399599 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of acrosome reaction and positive regulation of fertilization. Orthologous to human CCDC87 (coiled-coil domain containing 87). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male subfertility or infertility associated with severe sperm head defects, decreased initial sperm motility, impaired acrosome reaction, and loss of fertilizing capacity. [provided by MGI curators] |