Primary Identifier | MGI:2385695 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 225870 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables small GTPase binding activity. Acts upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Located in dendrite and neuronal cell body. Is expressed in brain; gonad; and thyroid gland. Orthologous to human RIN1 (Ras and Rab interactor 1). PHENOTYPE: Mice homozygous for disruptions in this gene display an enhanced conditioned response in cued conditioning protocols and avoidance learning tests. [provided by MGI curators] |