Primary Identifier | MGI:1932051 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 81601 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; histone acetyltransferase activity; and transcription coactivator activity. Involved in several processes, including nervous system development; positive regulation of regulatory T cell differentiation; and sperm DNA condensation. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Part of NuA4 histone acetyltransferase complex and transcription regulator complex. Is expressed in several structures, including central nervous system; eye; genitourinary system; hemolymphoid system gland; and limb. Orthologous to human KAT5 (lysine acetyltransferase 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit pre-implantation lethality. [provided by MGI curators] |