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Protein Coding Gene : Frmd8 FERM domain containing 8
Primary Identifier  MGI:1914707 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  67457
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within protein localization to plasma membrane. Predicted to be located in centriolar satellite; cytosol; and nucleoplasm. Predicted to be active in plasma membrane. Is expressed in several structures, including forelimb bud; otic capsule; and skeleton. Orthologous to several human genes including FRMD8 (FERM domain containing 8).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile. Mice homozygous for a conditional allele activated in the intestine exhibit increased AOM/DSS-induced colitis and adenoma formation. [provided by MGI curators]
  • synonyms:
  • FERM domain containing 8,
  • MGI:1916845,
  • 4931429L16Rik,
  • MGI:1918246,
  • expressed sequence AU018809,
  • RIKEN cDNA 4931429L16 gene,
  • 2310035N23Rik,
  • iTAP,
  • 1200004M23Rik,
  • AU018809,
  • RIKEN cDNA 2310035N23 gene,
  • MGI:2147645,
  • RIKEN cDNA 1200004M23 gene,
  • Frmd8
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