Primary Identifier | MGI:1352481 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 29805 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Is expressed in several structures, including liver; renal cortex; seminiferous tubule; telencephalon; and thymus. Orthologous to human ZNHIT2 (zinc finger HIT-type containing 2). PHENOTYPE: Mice homozygous for a knock-out allele show failure of in vitro blastocyst hatching and embryonic lethality during peri-implantation stages with fragmented DNA and abnormal inner cell mass, primitive endoderm, and trophectoderm morphology. [provided by MGI curators] |