Primary Identifier | MGI:1095403 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 22668 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Acts upstream of or within several processes, including Leydig cell differentiation; male sex determination; and nuclear body organization. Located in nuclear body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and sensory organ. Orthologous to human SF1 (splicing factor 1). PHENOTYPE: Mice heterozygous for a gene trapped allele exhibit embryonic lethalilty prior to E8.5. Mice heterozygous for a gene trapped allele exhibit increased incidence of chemically induced tumors. [provided by MGI curators] |