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Protein Coding Gene : Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12
Primary Identifier  MGI:1195269 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  20521
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables urate transmembrane transporter activity. Involved in urate transport. Located in brush border membrane. Is expressed in central nervous system; dorsal root ganglion; male reproductive gland or organ; metanephros; and retina layer. Orthologous to human SLC22A12 (solute carrier family 22 member 12).
PHENOTYPE: Mice homozygous for a null allele exhibit increased urinary urate levels and altered urine and plasma metabolite composition. [provided by MGI curators]
  • synonyms:
  • Rst,
  • AI987855,
  • Slc22a12,
  • expressed sequence AI987855,
  • Slc22al2,
  • MGI:2147622,
  • solute carrier family 22 (organic anion/cation transporter), member 12,
  • URAT1,
  • solute carrier family 22 (organic cation transporter)-like 2
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