Primary Identifier | MGI:1859854 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 104383 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity and transcription corepressor activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; retina; and skeleton. Orthologous to human RCOR2 (REST corepressor 2). PHENOTYPE: Mice homozygous for neuronal specific conditional loss of expression display impaired neurogenesis and neuronal precursor cell proliferation resulting in a thin cerebral cortex. [provided by MGI curators] |