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Protein Coding Gene : Spindoc spindlin interactor and repressor of chromatin binding

Primary Identifier  MGI:2147611 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  68229
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus and site of DNA damage. Orthologous to human SPINDOC (spindlin interactor and repressor of chromatin binding).
PHENOTYPE: Mice homozygous for null mutations of this gene are viable but exhibit decreased body weight, reduced levels of PARylation, and increased sensitivity to ionizing radiation. [provided by MGI curators]
  • synonyms:
  • Spindoc,
  • MGI:6108113,
  • expressed sequence AI846148,
  • spindlin interactor and repressor of chromatin binding,
  • AI846148

Features --> Cross References

Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For