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Protein Coding Gene : Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Primary Identifier  MGI:96955 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  17254
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein homodimerization activity. Involved in L-leucine transport. Located in apical pole of neuron and plasma membrane. Is active in synapse. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human SLC3A2 (solute carrier family 3 member 2).
PHENOTYPE: Homozygous mutant mice display embryonic lethality. Mice homozygous for a conditional allele activated in the intestinal epithelia exhibit resistance to decreased susceptibility to induced colitis and colitis-associated cancer. [provided by MGI curators]
  • synonyms:
  • Cd98,
  • MGD-MRK-12179,
  • Mgp-2hc,
  • MGI:106597,
  • MGD-MRK-12016,
  • lymphocyte antigen m10,
  • MGD-MRK-35053,
  • Ly-m10,
  • solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2,
  • Slc3a2,
  • AI314110,
  • MGD-MRK-11948,
  • Ly10,
  • Ly-10,
  • Mdu1,
  • MGI:2147500,
  • CD98 antigen,
  • MGD-MRK-12223,
  • expressed sequence AI314110,
  • MGD-MRK-12009,
  • lymphocyte antigen 10,
  • antigen identified by monoclonal antibodies 4F2,
  • 4F2HC
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