Primary Identifier | MGI:102704 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 14704 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G-protein beta-subunit binding activity and GTPase activity. Predicted to be involved in G protein-coupled receptor signaling pathway and positive regulation of cytosolic calcium ion concentration. Located in cell body; dendrite; and postsynaptic density. Is active in synapse. Is expressed in several structures, including gut; nervous system; oocyte; renal vasculature; and sensory organ. Orthologous to human GNG3 (G protein subunit gamma 3). PHENOTYPE: Homozygous null mice display handling- and noise-induced seizures resulting in premature death and reduced growth. Female homozygotes also display reduced inguinal and retroperitoneal fat pads. [provided by MGI curators] |