| Primary Identifier | MGI:98919 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 22287 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable polychlorinated biphenyl binding activity. Acts upstream of or within negative regulation of T cell proliferation; regulation of gene expression; and regulation of inflammatory response. Located in cytoplasm. Is expressed in heart and respiratory system. Used to study IgA glomerulonephritis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; asthma; and glomerulonephritis. Orthologous to human SCGB1A1 (secretoglobin family 1A member 1). PHENOTYPE: Homozygotes for targeted null mutations exhibit progressive renal glomerular disease characterized by proteinuria and hypocalcemia, necrotic pancreatic foci, reduced pulmonary neuroendocrine bodies, weight loss, cachexia, and premature mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
