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Protein Coding Gene : Incenp inner centromere protein
Primary Identifier  MGI:1313288 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  16319
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable molecular function activator activity. Predicted to be involved in meiotic spindle midzone assembly; metaphase chromosome alignment; and mitotic cytokinesis. Located in several cellular components, including chromocenter; midbody; and synaptonemal complex. Is expressed in brain ventricular layer; cerebral cortex subventricular zone; and heart. Orthologous to human INCENP (inner centromere protein).
PHENOTYPE: Homozygous mutant embryos die before E8.5. Embryonic cells exhibit abnormal nuclei and abberent mitosis. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2700067E22 gene,
  • MGI:1919833,
  • 2700067E22Rik,
  • C77457,
  • Incenp,
  • expressed sequence C77457,
  • MGI:2147646,
  • expressed sequence AU019509,
  • AU019509,
  • MGI:2147779,
  • inner centromere protein
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Disease

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