Primary Identifier | MGI:1930079 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 56473 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables stearoyl-CoA 9-desaturase activity. Predicted to be involved in arachidonate metabolite production involved in inflammatory response; lipid metabolic process; and positive regulation of cellular response to oxidative stress. Predicted to be located in membrane. Is expressed in several structures, including adrenal gland; genitourinary system; nervous system; and retina. Orthologous to human FADS2 (fatty acid desaturase 2). PHENOTYPE: Mice homozygous for a null allele display absence of long-chain polyunsaturated fatty acids, infertility, arrest of spermiogenesis and folliculogenesis, and impaired platelet function. [provided by MGI curators] |