| Primary Identifier | MGI:1923517 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 76267 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acyl-CoA delta5-desaturase activity. Predicted to be involved in arachidonate metabolic process; cellular response to starvation; and unsaturated fatty acid biosynthetic process. Predicted to act upstream of or within long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human FADS1 (fatty acid desaturase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit arachidonic acid deficiency with premature lethality and altered prostaglandin levels. Heterozygous mice exhibit an intermediate phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
