| Primary Identifier | MGI:1929691 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 65221 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables peptidoglycan transmembrane transporter activity. Involved in peptidoglycan transport and positive regulation of nucleotide-binding activity oligomerization domain containing 2 signaling pathway. Located in endosome membrane and lysosomal membrane. Is expressed in several structures, including brain; gut; hemolymphoid system; liver lobe; and testis. Orthologous to human SLC15A3 (solute carrier family 15 member 3). PHENOTYPE: The gene is involved in pathogen sensing by dendritic cells. Homozygous KO results in a reduction of the number of these cells displaying tubular endo-lysosomes after LPS treatment. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
