| Primary Identifier | MGI:2147810 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 98170 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein homodimerization activity. Acts upstream of or within negative regulation of protein catabolic process; positive regulation of Wnt protein secretion; and positive regulation of Wnt signaling pathway. Located in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; limb bud; lung; and spinal ganglion. Orthologous to human TMEM132A (transmembrane protein 132A). PHENOTYPE: Mice homozygous for a knockout allele die at birth exhibiting a range of malformations, including spina bifida, caudal body truncation, underdeveloped limb buds, forelimb syndactyly, lung and renal defects, and a shortened colon. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
