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Protein Coding Gene : Prpf19 pre-mRNA processing factor 19

Primary Identifier  MGI:106247 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  28000
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Predicted to enable identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in proteasomal protein catabolic process. Acts upstream of or within several processes, including inner cell mass cell proliferation; positive regulation of astrocyte differentiation; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19).
PHENOTYPE: Mice homozygous for a null allele die prior to implantation and have defective cell proliferation. [provided by MGI curators]
  • synonyms:
  • AA617263,
  • D19Wsu55e,
  • PSO4,
  • AL024362,
  • Prp19,
  • pre-mRNA processing factor 19,
  • Prpf19,
  • MGI:2147631,
  • MGI:2147181,
  • expressed sequence AL024362,
  • Snev,
  • MGD-MRK-33939,
  • DNA segment, Chr 19, Wayne State University 55, expressed,
  • PRP19/PSO4 homolog (S. cerevisiae),
  • expressed sequence AA617263

Features --> Cross References

Genome

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0 Exons

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

10 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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