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Protein Coding Gene : Zp1 zona pellucida glycoprotein 1
Primary Identifier  MGI:103073 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  22786
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable acrosin binding activity. Predicted to be a structural constituent of egg coat. Predicted to be involved in binding activity of sperm to zona pellucida and prevention of polyspermy. Located in collagen-containing extracellular matrix. Is expressed in early conceptus; ovary; and secondary oocyte. Orthologous to human ZP1 (zona pellucida glycoprotein 1).
PHENOTYPE: Female homozygous mutants produce oocytes with abnormal zona pellucida. Fecunditiy is significantly reduced, probably due to precocious hatching. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-23937,
  • zona pellucida glycoprotein 1,
  • Zp1
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