Primary Identifier | MGI:1916024 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 68774 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane and trans-Golgi network. Orthologous to several human genes including MS4A6A (membrane spanning 4-domains A6A). PHENOTYPE: Homozygous null mice exhibit decreased susceptibility to LPS-induced endotoxin lethality with lower proinflammatory cytokine levels. [provided by MGI curators] |