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Protein Coding Gene : Gcnt1 glucosaminyl (N-acetyl) transferase 1, core 2

Primary Identifier  MGI:95676 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  14537
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Involved in core 2 O-glycan biosynthetic process and positive regulation of leukocyte tethering or rolling. Acts upstream of or within kidney morphogenesis and tissue morphogenesis. Predicted to be located in Golgi cisterna; extracellular space; and trans-Golgi network. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human GCNT1 (glucosaminyl (N-acetyl) transferase 1).
PHENOTYPE: Mice homozygous for disruptions in this allele display a grossly normal phenotype and are fertile. There are abnormalities in white blood cell counts and in inflammatory response however. [provided by MGI curators]
  • synonyms:
  • C2 GlcNAcT,
  • Gcnt1,
  • RIKEN cDNA 5630400D21 gene,
  • glucosaminyl (N-acetyl) transferase 1, core 2,
  • beta-1, 6-N-acetylglucosaminyltransferase,
  • MGD-MRK-10022,
  • IGnT,
  • 5630400D21Rik,
  • MGI:1918694

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0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

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4 Pathways

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Disease

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