| Primary Identifier | MGI:2443101 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 226025 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to act upstream of or within monoatomic cation transport. Predicted to be active in plasma membrane. Is expressed in cochlea; liver; nervous system; and retina. Used to study cataract and microphthalmia. Human ortholog(s) of this gene implicated in cataract. Orthologous to human TRPM3 (transient receptor potential cation channel subfamily M member 3). PHENOTYPE: Homozygous knockout leads to impaired thermal and chemical nociception. Homozygous KO also results in small eyes and lenses, while a specific point mutation additionally leads to cataracts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
