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Protein Coding Gene : Insl6 insulin-like 6
Primary Identifier  MGI:1351595 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  27356
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable hormone activity. Acts upstream of or within several processes, including flagellated sperm motility; male gonad development; and spermatid development. Predicted to be located in extracellular region. Is expressed in several structures, including colon; gonad; heart; hemolymphoid system gland; and liver. Orthologous to human INSL6 (insulin like 6).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with male germ cell apoptosis and reduced sperm motility. [provided by MGI curators]
  • synonyms:
  • insulin-like 6,
  • Insl6,
  • relaxin/insulin-like factor 1,
  • RIF1
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