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Protein Coding Gene : Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein

Primary Identifier  MGI:1915009 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  67759
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within positive regulation of plasminogen activation. Located in plasma membrane. Is expressed in thymus primordium. Orthologous to human PLGRKT (plasminogen receptor with a C-terminal lysine).
PHENOTYPE: Mice homozygous for a null allele exhibit reduced female body weight, reduced milk production leading to pup lethality, dermatitis, and reduced leukocyte recruitment. Heterozygotes exhibit an intermediate dermatitis phenotype. [provided by MGI curators]
  • synonyms:
  • plasminogen receptor, C-terminal lysine transmembrane protein,
  • RIKEN cDNA 5033414D02 gene,
  • MGI:2147620,
  • AI852040,
  • RIKEN cDNA 1110007H22 gene,
  • 1110007H22Rik,
  • Plg-RKT,
  • Plgrkt,
  • 5033414D02Rik,
  • MGI:1921089,
  • expressed sequence AI852040

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Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

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0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

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Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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