Primary Identifier | MGI:1915009 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 67759 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of plasminogen activation. Located in plasma membrane. Is expressed in thymus primordium. Orthologous to human PLGRKT (plasminogen receptor with a C-terminal lysine). PHENOTYPE: Mice homozygous for a null allele exhibit reduced female body weight, reduced milk production leading to pup lethality, dermatitis, and reduced leukocyte recruitment. Heterozygotes exhibit an intermediate dermatitis phenotype. [provided by MGI curators] |