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Protein Coding Gene : Pdcd1lg2 programmed cell death 1 ligand 2
Primary Identifier  MGI:1930125 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  58205
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within negative regulation of T cell proliferation and positive regulation of T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system epithelium; forebrain; nose; retina; and skin. Orthologous to human PDCD1LG2 (programmed cell death 1 ligand 2).
PHENOTYPE: Mice homozygous for disruptions in this gene have dendritic cells that display a diminished ability to activate CD4+ T cells. [provided by MGI curators]
  • synonyms:
  • PD-L2,
  • Pdcd1lg2,
  • RIKEN cDNA F730015O22 gene,
  • MGI:2442044,
  • F730015O22Rik,
  • programmed cell death 1 ligand 2,
  • B7-DC,
  • Btdc
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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