Primary Identifier | MGI:1932622 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 83410 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in brain and spinal cord. Orthologous to human CSTF2T (cleavage stimulation factor subunit 2 tau variant). PHENOTYPE: Male mice homozygous for a targeted null allele are infertile due to low sperm counts, significant developmental defects in spermiogenesis, and variable abnormalities in epididymal sperm morphology and motility consistent with oligoasthenoteratozoospermia. Homozygous null females are fertile. [provided by MGI curators] |