| Primary Identifier | MGI:1915229 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 67979 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP hydrolysis activity. Involved in learning or memory; negative regulation of glutamatergic synaptic transmission; and regulation of receptor internalization. Located in postsynaptic membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in central nervous system; ganglia; renal cortex; submandibular gland primordium; and thymus primordium. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body size, seizure, absent LTD, enhanced LTP, enhanced AMPA-mediated currents, and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
