Primary Identifier | MGI:99450 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 15957 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Involved in response to virus. Acts upstream of or within cellular response to interferon-alpha; cellular response to interferon-beta; and response to bacterium. Located in cytoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; eye; genitourinary system; and nervous system. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratricopeptide repeats 1B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered response to vesicular stomatitis virus (VSV) infection. [provided by MGI curators] |