| Primary Identifier | MGI:1858229 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 53412 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycogen binding activity; molecular adaptor activity; and protein phosphatase binding activity. Involved in glycogen biosynthetic process. Acts upstream of or within glycogen metabolic process. Is active in cytosol. Is expressed in genitourinary system; liver; and nasal capsule. Used to study type 2 diabetes mellitus. Orthologous to human PPP1R3C (protein phosphatase 1 regulatory subunit 3C). PHENOTYPE: Homozygous null mice are embyronic lethal. Heterozygotes have reduced glycogen stores, attenuated glycogen synthesis, glucose intolerance, hyperinsulinemia and insulin resistance. Mice homozygous for a different knock-out allele exhibit normal lifespan with enhanced whole body insulin sensitivity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
